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Metabolic Switching of Tumor Cells under Hypoxic Conditions in a Tumor-on-a-chip Model
Hypoxia switches the metabolism of tumor cells and induces drug resistance. Currently, no therapeutic exists that effectively and specifically targets hypoxic cells in tumors. Development of such therapeutics critically depends on the availability of in vitro models that accurately recapitulate hypo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231186/ https://www.ncbi.nlm.nih.gov/pubmed/32260396 http://dx.doi.org/10.3390/mi11040382 |