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αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors

The α9-containing nicotinic acetylcholine receptor (nAChR) is increasingly emerging as a new tumor target owing to its high expression specificity in breast cancer. αO-Conotoxin GeXIVA is a potent antagonist of α9α10 nAChR. Nevertheless, the anti-tumor effect of GeXIVA on breast cancer cells remains...

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Detalles Bibliográficos
Autores principales: Sun, Zhihua, Bao, Jiaolin, Zhangsun, Manqi, Dong, Shuai, Zhangsun, Dongting, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231225/
https://www.ncbi.nlm.nih.gov/pubmed/32272701
http://dx.doi.org/10.3390/md18040195