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Identification of High-Frequency Methylation Sites in RNF180 Promoter Region Affecting Expression and Their Relationship with Prognosis of Gastric Cancer

BACKGROUND: Ring finger protein 180 (RNF180) is a tumor suppressor gene regulated by promoter methylation. We previously demonstrated that the RNF180 promoter methylation could be a risk factor for gastric cancer (GC); and eight high-frequency hypermethylated CpG sites were associated with GC....

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Detalles Bibliográficos
Autores principales: Han, Fang, Liu, Shuang, Jing, Jingjing, Li, Hao, Yuan, Yuan, Sun, Li-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231750/
https://www.ncbi.nlm.nih.gov/pubmed/32494203
http://dx.doi.org/10.2147/CMAR.S246995