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Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling

BACKGROUND: Emerging evidence suggests that circular RNAs (circRNAs) are vital regulators in a range of cancers. “miRNA sponge” is the most reported role played by circRNAs in many tumors. The insulin-like growth factor (IGF) 1 pathway plays a key role in the development and progression of many canc...

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Detalles Bibliográficos
Autores principales: Chen, Zhi-Lei, Li, Xiang-Nan, Ye, Chun-Xiang, Chen, Hong-Yu, Wang, Zhen-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231768/
https://www.ncbi.nlm.nih.gov/pubmed/32494158
http://dx.doi.org/10.2147/OTT.S254133