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Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling
BACKGROUND: Emerging evidence suggests that circular RNAs (circRNAs) are vital regulators in a range of cancers. “miRNA sponge” is the most reported role played by circRNAs in many tumors. The insulin-like growth factor (IGF) 1 pathway plays a key role in the development and progression of many canc...
Autores principales: | Chen, Zhi-Lei, Li, Xiang-Nan, Ye, Chun-Xiang, Chen, Hong-Yu, Wang, Zhen-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231768/ https://www.ncbi.nlm.nih.gov/pubmed/32494158 http://dx.doi.org/10.2147/OTT.S254133 |
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