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p47phox deficiency impairs platelet function and protects mice against arterial and venous thrombosis

NADPH oxidase-derived reactive oxygen species (ROS) regulates platelet function and thrombosis. It remains controversial regarding NOX2’s role in platelet function. As a regulatory subunit for NOX2, whether p47phox regulates platelet function remains unclear. Our study intends to evaluate p47phox’s...

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Detalles Bibliográficos
Autores principales: Wang, Xiamin, Zhang, Sixuan, Ding, Yangyang, Tong, Huan, Xu, Xiaoqi, Wei, Guangyu, Chen, Yuting, Ju, Wen, Fu, Chunling, Qi, Kunming, Li, Zhenyu, Zeng, Lingyu, Xu, Kailin, Qiao, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231845/
https://www.ncbi.nlm.nih.gov/pubmed/32422541
http://dx.doi.org/10.1016/j.redox.2020.101569