Interleukin-6 trans-signaling inhibition prevents oxidative stress in a mouse model of early diabetic retinopathy

PURPOSE: Diabetic retinopathy (DR), a microvascular complication of diabetes, is the leading cause of visual disability and blindness in diabetic patients. Chronic hyperglycemia leads to increased oxidative stress and inflammation in the retina, resulting in microvascular damage. Our recent in vitro...

Descripción completa

Detalles Bibliográficos
Autores principales: Robinson, Rebekah, Srinivasan, Mukund, Shanmugam, Arul, Ward, Alexander, Ganapathy, Veena, Bloom, Justin, Sharma, Ashok, Sharma, Shruti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231846/
https://www.ncbi.nlm.nih.gov/pubmed/32422539
http://dx.doi.org/10.1016/j.redox.2020.101574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231846/
https://www.ncbi.nlm.nih.gov/pubmed/32422539
http://dx.doi.org/10.1016/j.redox.2020.101574

Ejemplares similares