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Interleukin-6 trans-signaling inhibition prevents oxidative stress in a mouse model of early diabetic retinopathy
PURPOSE: Diabetic retinopathy (DR), a microvascular complication of diabetes, is the leading cause of visual disability and blindness in diabetic patients. Chronic hyperglycemia leads to increased oxidative stress and inflammation in the retina, resulting in microvascular damage. Our recent in vitro...
Autores principales: | Robinson, Rebekah, Srinivasan, Mukund, Shanmugam, Arul, Ward, Alexander, Ganapathy, Veena, Bloom, Justin, Sharma, Ashok, Sharma, Shruti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231846/ https://www.ncbi.nlm.nih.gov/pubmed/32422539 http://dx.doi.org/10.1016/j.redox.2020.101574 |
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