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Development of an enzyme-linked immunosorbent assay for Keap1-Nrf2 interaction inhibitors identification
Development of Keap1–Nrf2 interaction inhibitors is a promising strategy for the discovery of therapeutic agents against oxidative stress-mediated diseases. Two motifs of Nrf2, ETGE and DLG motif, are responsible for Keap1-Nrf2 binding. Previously, ETGE peptide or ETGE-derived peptide-based approach...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231848/ https://www.ncbi.nlm.nih.gov/pubmed/32422542 http://dx.doi.org/10.1016/j.redox.2020.101573 |