Development of an enzyme-linked immunosorbent assay for Keap1-Nrf2 interaction inhibitors identification

Development of Keap1–Nrf2 interaction inhibitors is a promising strategy for the discovery of therapeutic agents against oxidative stress-mediated diseases. Two motifs of Nrf2, ETGE and DLG motif, are responsible for Keap1-Nrf2 binding. Previously, ETGE peptide or ETGE-derived peptide-based approach...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Xiao, Chu-Ying, Lin, Huang-Quan, Hu, Jian-Shu, Ip, Tsz-Ming, Chi-Cheong Wan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231848/
https://www.ncbi.nlm.nih.gov/pubmed/32422542
http://dx.doi.org/10.1016/j.redox.2020.101573

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