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IKZF3/Aiolos Is Associated with but Not Sufficient for the Expression of IL-10 by CD4(+) T Cells

The expression of anti-inflammatory IL-10 by CD4(+) T cells is indispensable for immune homeostasis, as it allows T cells to moderate their effector function. We previously showed that TNF-α blockade during T cell stimulation in CD4(+) T cell/monocyte cocultures resulted in maintenance of IL-10–prod...

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Detalles Bibliográficos
Autores principales: Ridley, Michael L., Fleskens, Veerle, Roberts, Ceri A., Lalnunhlimi, Sylvine, Alnesf, Aldana, O’Byrne, Aoife M., Steel, Kathryn J. A., Povoleri, Giovanni A. M., Sumner, Jonathan, Lavender, Paul, Taams, Leonie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231851/
https://www.ncbi.nlm.nih.gov/pubmed/32321757
http://dx.doi.org/10.4049/jimmunol.1901283