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Blood Outgrowth Endothelial Cells as a Cellular Carrier for Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Preclinical Models of Non-Small Cell Lung Cancer

Oncolytic viruses have demonstrated efficacy in numerous tumor models including non-small cell lung cancer (NSCLC). One limitation of viral therapy for metastatic lung cancer is that systemic administration can be hindered by complement and antiviral immunity. Thus, we investigated whether ex vivo-i...

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Detalles Bibliográficos
Autores principales: Patel, Manish R., Jacobson, Blake A., Ji, Yan, Hebbel, Robert P., Kratzke, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231872/
https://www.ncbi.nlm.nih.gov/pubmed/32422574
http://dx.doi.org/10.1016/j.tranon.2020.100782