All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation

High-throughput in vitro drug assays have been impacted by recent advances in human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) technology and by contact-free all-optical systems simultaneously measuring action potentials (APs) and Ca(2+) transients (CaTrs). Parallel computational...

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Detalles Bibliográficos
Autores principales: Paci, Michelangelo, Passini, Elisa, Klimas, Aleksandra, Severi, Stefano, Hyttinen, Jari, Rodriguez, Blanca, Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231889/
https://www.ncbi.nlm.nih.gov/pubmed/32298635
http://dx.doi.org/10.1016/j.bpj.2020.03.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231889/
https://www.ncbi.nlm.nih.gov/pubmed/32298635
http://dx.doi.org/10.1016/j.bpj.2020.03.018

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