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Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway

BACKGROUND: Angiogenesis plays an important role in the development of rheumatoid arthritis (RA), which increases the supply of nutrients, cytokines, and inflammatory cells to the synovial membrane. Genistein (GEN), a soy-derived isoflavone, has been validated that can effectively inhibit the angiog...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Xiang, Huang, Huan, Chen, Jian-Hai, Zhang, Tian-Tian, Zhu, Guo-Yuan, Zheng, Zheng-Tan, Lin, Jie-Tao, Hu, Yi-Ping, Zhang, Yong, Bai, Xue-Ling, Wang, Yan, Xu, Zhan-Wang, Song, Bing, Mao, Yi-Ying, Yang, Fei, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231959/
https://www.ncbi.nlm.nih.gov/pubmed/32440504
http://dx.doi.org/10.1016/j.jot.2019.07.007