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Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan

BACKGROUND: Primary tumor location is a critical prognostic factor that also impacts the efficacy of anti-epidermal growth factor receptor (EGFR) therapy in wild-type RAS (KRAS/NRAS) metastatic colorectal cancer (CRC). However, the association between the incidence of BRAF and phosphatidylinositol-4...

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Detalles Bibliográficos
Autores principales: Taniguchi, Hiroya, Uehara, Keisuke, Nakayama, Goro, Nakayama, Hiroshi, Aiba, Toshisada, Hattori, Norifumi, Kataoka, Masato, Nakano, Yasuyuki, Kawase, Yoshihisa, Okochi, Osamu, Matsuoka, Hiroshi, Utsunomiya, Setsuo, Sakamoto, Eiji, Mori, Yoshinori, Umeda, Shinichi, Shikano, Toshio, Komori, Koji, Tajika, Masahiro, Kadowaki, Shigenori, Muro, Kei, Yatabe, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232108/
https://www.ncbi.nlm.nih.gov/pubmed/32428838
http://dx.doi.org/10.1016/j.tranon.2020.100786