The Novel Phospholipid Mimetic KPC34 Is Highly Active Against Acute Myeloid Leukemia with Activated Protein Kinase C()

Acute myeloid leukemia (AML) is an aggressive malignancy with poor outcomes. Nucleoside analogs are subject to resistance mechanisms including downregulation of equilibrative nucleoside transporter (ENT1) and deoxycytidine kinase (dCK). KPC34 is a novel phospholipid mimetic that when cleaved by phos...

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Detalles Bibliográficos
Autores principales: Alexander, Peter M., Kucera, Gregory L., Pladna, Kristin M., Pardee, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232109/
https://www.ncbi.nlm.nih.gov/pubmed/32428837
http://dx.doi.org/10.1016/j.tranon.2020.100780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232109/
https://www.ncbi.nlm.nih.gov/pubmed/32428837
http://dx.doi.org/10.1016/j.tranon.2020.100780

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