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Cytomegalovirus Strain TB40/E Restrictions and Adaptations to Growth in ARPE-19 Epithelial Cells

Despite displaying broad tropism in vivo, human cytomegalovirus (CMV) contained in bodily fluids replicates inefficiently in most cultured cell types except fibroblasts. As propagation in fibroblasts leads to the accumulation of genomic changes, a number of strains were generated by serial passaging...

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Detalles Bibliográficos
Autores principales: Vo, Mai, Aguiar, Alexis, McVoy, Michael A., Hertel, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232150/
https://www.ncbi.nlm.nih.gov/pubmed/32344555
http://dx.doi.org/10.3390/microorganisms8040615