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Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules

HIV-1 capsid protein (CA) plays an important role in many steps of viral replication and represents an appealing antiviral target. Several CA-targeting small molecules of various chemotypes have been studied, but the peptidomimetic PF74 has drawn particular interest due to its potent antiviral activ...

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Detalles Bibliográficos
Autores principales: Vernekar, Sanjeev Kumar V., Sahani, Rajkumar Lalji, Casey, Mary C., Kankanala, Jayakanth, Wang, Lei, Kirby, Karen A., Du, Haijuan, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232165/
https://www.ncbi.nlm.nih.gov/pubmed/32316297
http://dx.doi.org/10.3390/v12040452