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APETx-Like Peptides from the Sea Anemone Heteractis crispa, Diverse in Their Effect on ASIC1a and ASIC3 Ion Channels

Currently, five peptide modulators of acid-sensing ion channels (ASICs) attributed to structural class 1b of sea anemone toxins have been described. The APETx2 toxin is the first and most potent ASIC3 inhibitor, so its homologs from sea anemones are known as the APETx-like peptides. We have discover...

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Detalles Bibliográficos
Autores principales: Kalina, Rimma S., Koshelev, Sergey G., Zelepuga, Elena A., Kim, Natalia Y., Kozlov, Sergey A., Kozlovskaya, Emma P., Monastyrnaya, Margarita M., Gladkikh, Irina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232172/
https://www.ncbi.nlm.nih.gov/pubmed/32326130
http://dx.doi.org/10.3390/toxins12040266