High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi

Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, affects between 6 and 7 million people worldwide, with an estimated 300,000 to 1 million of these cases in the United States. In the chronic phase of infection, T. cruzi can cause severe gastrointestinal and cardiac disease, whi...

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Detalles Bibliográficos
Autores principales: Bernatchez, Jean A., Chen, Emily, Hull, Mitchell V., McNamara, Case W., McKerrow, James H., Siqueira-Neto, Jair L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232187/
https://www.ncbi.nlm.nih.gov/pubmed/32224991
http://dx.doi.org/10.3390/microorganisms8040472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232187/
https://www.ncbi.nlm.nih.gov/pubmed/32224991
http://dx.doi.org/10.3390/microorganisms8040472

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