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High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi
Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, affects between 6 and 7 million people worldwide, with an estimated 300,000 to 1 million of these cases in the United States. In the chronic phase of infection, T. cruzi can cause severe gastrointestinal and cardiac disease, whi...
Autores principales: | Bernatchez, Jean A., Chen, Emily, Hull, Mitchell V., McNamara, Case W., McKerrow, James H., Siqueira-Neto, Jair L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232187/ https://www.ncbi.nlm.nih.gov/pubmed/32224991 http://dx.doi.org/10.3390/microorganisms8040472 |
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