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Engineering Improves Enzymatic Synthesis of L-Tryptophan by Tryptophan Synthase from Escherichia coli

To improve the thermostability of tryptophan synthase, the molecular modification of tryptophan synthase was carried out by rational molecular engineering. First, B-FITTER software was used to analyze the temperature factor (B-factor) of each amino acid residue in the crystal structure of tryptophan...

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Detalles Bibliográficos
Autores principales: Xu, Lisheng, Han, Fangkai, Dong, Zeng, Wei, Zhaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232222/
https://www.ncbi.nlm.nih.gov/pubmed/32260519
http://dx.doi.org/10.3390/microorganisms8040519