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Engineering Improves Enzymatic Synthesis of L-Tryptophan by Tryptophan Synthase from Escherichia coli
To improve the thermostability of tryptophan synthase, the molecular modification of tryptophan synthase was carried out by rational molecular engineering. First, B-FITTER software was used to analyze the temperature factor (B-factor) of each amino acid residue in the crystal structure of tryptophan...
Autores principales: | Xu, Lisheng, Han, Fangkai, Dong, Zeng, Wei, Zhaojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232222/ https://www.ncbi.nlm.nih.gov/pubmed/32260519 http://dx.doi.org/10.3390/microorganisms8040519 |
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