Hepatitis C Virus Proteins Core and NS5A Are Highly Sensitive to Oxidative Stress-Induced Degradation after eIF2α/ATF4 Pathway Activation

Hepatitis C virus (HCV) infection is accompanied by increased oxidative stress and endoplasmic reticulum stress as a consequence of viral replication, production of viral proteins, and pro-inflammatory signals. To overcome the cellular stress, hepatocytes have developed several adaptive mechanisms l...

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Detalles Bibliográficos
Autores principales: Ríos-Ocampo, W. Alfredo, Navas, María-Cristina, Buist-Homan, Manon, Faber, Klaas Nico, Daemen, Toos, Moshage, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232227/
https://www.ncbi.nlm.nih.gov/pubmed/32283772
http://dx.doi.org/10.3390/v12040425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232227/
https://www.ncbi.nlm.nih.gov/pubmed/32283772
http://dx.doi.org/10.3390/v12040425

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