Mice expressing an XRCC1 truncated protein are at increased risk for insulin resistance

Insulin resistance is a metabolic disorder that is highly prevalent in older populations. Mice expressing a truncated X-ray repair cross-complementing protein 1 (XRCC1tp) have normal repair of single-stranded breaks (SSBs) but are sensitive to alkylating agents. XRCC1tp mice thus provide a model to...

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Detalles Bibliográficos
Autores principales: Sharma, Kavita, Wu, Jinzi, Lee, Shu Xian, Ladiges, Warren C., Goh, Jorming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Animal Model Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232285/
https://www.ncbi.nlm.nih.gov/pubmed/32477470
http://dx.doi.org/10.1080/20010001.2019.1603517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232285/
https://www.ncbi.nlm.nih.gov/pubmed/32477470
http://dx.doi.org/10.1080/20010001.2019.1603517

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