Cargando…

An In Silico Target Fishing Approach to Identify Novel Ochratoxin A Hydrolyzing Enzyme

Ochratoxin A (OTA), a mycotoxin that is of utmost concern in food and feed safety, is produced by fungal species that mainly belong to the Aspergillus and Penicillium genera. The development of mitigation strategies to reduce OTA content along the supply chains is key to ensuring safer production of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dellafiora, Luca, Gonaus, Christoph, Streit, Barbara, Galaverna, Gianni, Moll, Wulf-Dieter, Vogtentanz, Gudrun, Schatzmayr, Gerd, Dall’Asta, Chiara, Prasad, Shreenath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232302/ https://www.ncbi.nlm.nih.gov/pubmed/32316122 http://dx.doi.org/10.3390/toxins12040258

Ejemplares similares

Toxicodynamics of Mycotoxins in the Framework of Food Risk Assessment—An In Silico Perspective
por: Dellafiora, Luca, et al.
Publicado: (2018)

Degradation of Aflatoxins by Means of Laccases from Trametes versicolor: An In Silico Insight
por: Dellafiora, Luca, et al.
Publicado: (2017)

On the Mechanism of Action of Anti-Inflammatory Activity of Hypericin: An In Silico Study Pointing to the Relevance of Janus Kinases Inhibition
por: Dellafiora, Luca, et al.
Publicado: (2018)

An In Silico Framework to Mine Bioactive Peptides from Annotated Proteomes: A Case Study on Pancreatic Alpha Amylase Inhibitory Peptides from Algae and Cyanobacteria
por: Pedroni, Lorenzo, et al.
Publicado: (2022)

Alternaria toxins as casein kinase 2 inhibitors and possible consequences for estrogenicity: a hybrid in silico/in vitro study
por: Aichinger, Georg, et al.
Publicado: (2020)

Toolbox for the Extraction and Quantification of Ochratoxin A and Ochratoxin Alpha Applicable for Different Pig and Poultry Matrices
por: Streit, Barbara, et al.
Publicado: (2022)

A Structural Study on the Listeria Monocytogenes Internalin A—Human E-cadherin Interaction: A Molecular Tool to Investigate the Effects of Missense Mutations
por: Dellafiora, Luca, et al.
Publicado: (2020)

Ergot alkaloids: From witchcraft till in silico analysis. Multi-receptor analysis of ergotamine metabolites
por: Dellafiora, Luca, et al.
Publicado: (2015)

Co-Occurrence and Combinatory Effects of Alternaria Mycotoxins and Other Xenobiotics of Food Origin: Current Scenario and Future Perspectives
por: Crudo, Francesco, et al.
Publicado: (2019)

Thinking Out of the Box: On the Ability of Zea mays L. to Biotrasform Aflatoxin B1 Into Its Modified Forms
por: Righetti, Laura, et al.
Publicado: (2021)

Enzyme characteristics of aminotransferase FumI of Sphingopyxis sp. MTA144 for deamination of hydrolyzed fumonisin B(1)
por: Hartinger, Doris, et al.
Publicado: (2011)

Enhancement of solubility in Escherichia coli and purification of an aminotransferase from Sphingopyxis sp. MTA144 for deamination of hydrolyzed fumonisin B(1)
por: Hartinger, Doris, et al.
Publicado: (2010)

Forthcoming Challenges in Mycotoxins Toxicology Research for Safer Food—A Need for Multi-Omics Approach
por: Dellafiora, Luca, et al.
Publicado: (2017)

Recent Advances and Future Challenges in Modified Mycotoxin Analysis: Why HRMS Has Become a Key Instrument in Food Contaminant Research
por: Righetti, Laura, et al.
Publicado: (2016)

Cyclodextrins Can Entrap Zearalenone-14-Glucoside: Interaction of the Masked Mycotoxin with Cyclodextrins and Cyclodextrin Bead Polymer
por: Faisal, Zelma, et al.
Publicado: (2019)

A Computational Understanding of Inter-Individual Variability in CYP2D6 Activity to Investigate the Impact of Missense Mutations on Ochratoxin A Metabolism
por: Dorne, Jean Lou C. M., et al.
Publicado: (2022)

Risk–benefit assessment of shifting from traditional meat‐based diets to alternative dietary patterns
por: Mihalache, Octavian Augustin, et al.
Publicado: (2022)

Rice Bran By-Product: From Valorization Strategies to Nutritional Perspectives
por: Spaggiari, Marco, et al.
Publicado: (2021)

In silico study on the Hepatitis E virus RNA Helicase and its inhibition by silvestrol, rocaglamide and other flavagline compounds
por: Pedroni, Lorenzo, et al.
Publicado: (2022)

Plant organ cultures as masked mycotoxin biofactories: Deciphering the fate of zearalenone in micropropagated durum wheat roots and leaves
por: Righetti, Laura, et al.
Publicado: (2017)

Plant biotransformation of T2 and HT2 toxin in cultured organs of Triticum durum Desf
por: Righetti, Laura, et al.
Publicado: (2019)

In Silico Approaches Applied to the Study of Peptide Analogs of Ile-Pro-Ile in Relation to Their Dipeptidyl Peptidase IV Inhibitory Properties
por: Nongonierma, Alice B., et al.
Publicado: (2018)

Durum Wheat (Triticum Durum Desf.) Lines Show Different Abilities to Form Masked Mycotoxins under Greenhouse Conditions
por: Cirlini, Martina, et al.
Publicado: (2013)

Untargeted Metabolomics of Meat Digests: Its Potential to Differentiate Pork Depending on the Feeding Regimen
por: Cirlini, Martina, et al.
Publicado: (2023)

Simulated Gastrointestinal Digestion of Cocoa: Detection of Resistant Peptides and In Silico/In Vitro Prediction of Their Ace Inhibitory Activity
por: Marseglia, Angela, et al.
Publicado: (2019)

Risk assessment of ochratoxin A in food
por: Schrenk, Dieter, et al.
Publicado: (2020)

Evolutionary Wheat Populations in High-Quality Breadmaking as a Tool to Preserve Agri-Food Biodiversity
por: Spaggiari, Marco, et al.
Publicado: (2022)

Characterization and Discrimination of Ancient Grains: A Metabolomics Approach
por: Righetti, Laura, et al.
Publicado: (2016)

Open Field Study of Some Zea mays Hybrids, Lipid Compounds and Fumonisins Accumulation
por: Giorni, Paola, et al.
Publicado: (2015)

Rapid and Comprehensive Evaluation of (Poly)phenolic Compounds in Pomegranate (Punica granatum L.) Juice by UHPLC-MS(n)
por: Mena, Pedro, et al.
Publicado: (2012)

A molecular insight into the lipid changes of pig Longissimus thoracis muscle following dietary supplementation with functional ingredients
por: Rocchetti, Gabriele, et al.
Publicado: (2022)

Biotransformation of the Mycotoxin Zearalenone to its Metabolites Hydrolyzed Zearalenone (HZEN) and Decarboxylated Hydrolyzed Zearalenone (DHZEN) Diminishes its Estrogenicity In Vitro and In Vivo
por: Fruhauf, Sebastian, et al.
Publicado: (2019)

A Computational Inter-Species Study on Safrole Phase I Metabolism-Dependent Bioactivation: A Mechanistic Insight into the Study of Possible Differences among Species
por: Pedroni, Lorenzo, et al.
Publicado: (2023)

Dose-Dependent Effects on Sphingoid Bases and Cytokines in Chickens Fed Diets Prepared with Fusarium Verticillioides Culture Material Containing Fumonisins
por: Grenier, Bertrand, et al.
Publicado: (2015)

Mechanistic Insights into Angiotensin I-Converting Enzyme Inhibitory Tripeptides to Decipher the Chemical Basis of Their Activity
por: Lammi, Carmen, et al.
Publicado: (2022)

MicroRNAs in porcine uterus and serum are affected by zearalenone and represent a new target for mycotoxin biomarker discovery
por: Grenier, Bertrand, et al.
Publicado: (2019)

Interaction of Mycotoxin Alternariol with Serum Albumin
por: Fliszár-Nyúl, Eszter, et al.
Publicado: (2019)

Structural Similarity with Cholesterol Reveals Crucial Insights into Mechanisms Sustaining the Immunomodulatory Activity of the Mycotoxin Alternariol
por: Del Favero, Giorgia, et al.
Publicado: (2020)

In vitro interactions of Alternaria mycotoxins, an emerging class of food contaminants, with the gut microbiota: a bidirectional relationship
por: Crudo, Francesco, et al.
Publicado: (2021)

Detoxification of the Fumonisin Mycotoxins in Maize: An Enzymatic Approach
por: Alberts, Johanna, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_o9uddrmbpkpkvm9ovpc14fvh30