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Status of Asp29 and Asp40 in the Interaction of Naja atra Cardiotoxins with Lipid Bilayers

It is widely accepted that snake venom cardiotoxins (CTXs) target the plasma membranes of cells. In the present study, we investigated the role of Asp residues in the interaction of Naja atra cardiotoxin 1 (CTX1) and cardiotoxin 3 (CTX3) with phospholipid bilayers using chemical modification. CTX1 c...

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Detalles Bibliográficos
Autores principales: Wu, Guan-Lin, Shi, Yi-Jun, Huang, Chia-Hui, Lee, Yuan-Chin, Wang, Liang-Jun, Chiou, Jing-Ting, Lu, Chi-Yu, Chang, Long-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232319/
https://www.ncbi.nlm.nih.gov/pubmed/32325789
http://dx.doi.org/10.3390/toxins12040262