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2′, 5′-Oligoadenylate Synthetase 2 (OAS2) Inhibits Zika Virus Replication through Activation of Type Ι IFN Signaling Pathway

Background: 2′, 5′-oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore the effect of OAS2 on ZIKV replication and its underlying mechanism....

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Detalles Bibliográficos
Autores principales: Liao, Xinzhong, Xie, He, Li, Shilin, Ye, Haiyan, Li, Shuang, Ren, Kai, Li, Yujia, Xu, Min, Lin, Wenyu, Duan, Xiaoqiong, Yang, Chunhui, Chen, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232345/
https://www.ncbi.nlm.nih.gov/pubmed/32276512
http://dx.doi.org/10.3390/v12040418