Amino Acid Substitutions in Positions 385 and 393 of the Hydrophobic Region of VP4 May Be Associated with Rotavirus Attenuation and Cell Culture Adaptation

Rotaviruses (RVs) are the leading cause of the acute viral gastroenteritis in young children and livestock animals worldwide. Although live attenuated vaccines have been applied to control RV infection for many years, the underlying mechanisms of RV attenuation following cell culture adaption are un...

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Detalles Bibliográficos
Autores principales: Guo, Yusheng, Wentworth, David E., Stucker, Karla M., Halpin, Rebecca A., Lam, Ham Ching, Marthaler, Douglas, Saif, Linda J., Vlasova, Anastasia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232350/
https://www.ncbi.nlm.nih.gov/pubmed/32272747
http://dx.doi.org/10.3390/v12040408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232350/
https://www.ncbi.nlm.nih.gov/pubmed/32272747
http://dx.doi.org/10.3390/v12040408

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