Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane

Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever. MARV encodes seven proteins, including VP40 (mVP40), a matrix protein that interacts with the cytoplasmic leaflet of the host cell plasma membrane. VP40 traffics to the pla...

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Detalles Bibliográficos
Autores principales: Wijesinghe, Kaveesha J., McVeigh, Luke, Husby, Monica L., Bhattarai, Nisha, Ma, Jia, Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232359/
https://www.ncbi.nlm.nih.gov/pubmed/32344654
http://dx.doi.org/10.3390/v12040482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232359/
https://www.ncbi.nlm.nih.gov/pubmed/32344654
http://dx.doi.org/10.3390/v12040482

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