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The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation

Macrodomains, enzymes that remove ADP-ribose from proteins, are encoded by several families of RNA viruses and have recently been shown to counter innate immune responses to virus infection. ADP-ribose is covalently attached to target proteins by poly-ADP-ribose polymerases (PARPs), using nicotinami...

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Detalles Bibliográficos
Autores principales: Alhammad, Yousef M. O., Fehr, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232374/
https://www.ncbi.nlm.nih.gov/pubmed/32244383
http://dx.doi.org/10.3390/v12040384