RNA Binding Suppresses Tsg101 Recognition of Ub-Modified Gag and Facilitates Recruitment to the Plasma Membrane

The ESCRT-I factor Tsg101 is essential for sorting endocytic cargo and is exploited by viral pathogens to facilitate egress from cells. Both the nucleocapsid (NC) domain and p6 domain in HIV-1 Gag contribute to recruitment of the protein. However, the role of NC is unclear when the P(S/T)AP motif in...

Descripción completa

Detalles Bibliográficos
Autores principales: Watanabe, Susan M., Strickland, Madeleine, Tjandra, Nico, Carter, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232412/
https://www.ncbi.nlm.nih.gov/pubmed/32326417
http://dx.doi.org/10.3390/v12040447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232412/
https://www.ncbi.nlm.nih.gov/pubmed/32326417
http://dx.doi.org/10.3390/v12040447

Ejemplares similares