RNA-Binding Domains of Heterologous Viral Proteins Substituted for Basic Residues in the RSV Gag NC Domain Restore Specific Packaging of Genomic RNA

The Rous sarcoma virus Gag polyprotein transiently traffics through the nucleus, which is required for efficient incorporation of the viral genomic RNA (gRNA) into virus particles. Packaging of gRNA is mediated by two zinc knuckles and basic residues located in the nucleocapsid (NC) domain in Gag. T...

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Detalles Bibliográficos
Autores principales: Rice, Breanna L., Lochmann, Timothy L., Parent, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232437/
https://www.ncbi.nlm.nih.gov/pubmed/32230826
http://dx.doi.org/10.3390/v12040370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232437/
https://www.ncbi.nlm.nih.gov/pubmed/32230826
http://dx.doi.org/10.3390/v12040370

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