Cargando…

A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication

PB10 IgG(1), a monoclonal antibody (MAb) directed against an immunodominant epitope on the enzymatic subunit (RTA) of ricin toxin (RT), has been shown to passively protect mice and non-human primates from an aerosolized lethal-dose RT challenge. However, it was recently demonstrated that the therape...

Descripción completa

Detalles Bibliográficos
Autores principales: Rong, Yinghui, Pauly, Michael, Guthals, Adrian, Pham, Henry, Ehrbar, Dylan, Zeitlin, Larry, Mantis, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232472/
https://www.ncbi.nlm.nih.gov/pubmed/32235318
http://dx.doi.org/10.3390/toxins12040215