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Successive Passage In Vitro Led to Lower Virulence and Higher Titer of A Variant Porcine Epidemic Diarrhea Virus

A highly virulent porcine epidemic diarrhea virus (PEDV) appeared in China and spread rapidly to neighbor countries, which have led to great economic losses to the pig industry. In the present study, we isolated a PEDV using Vero cells and serially propagated 100 passages. PEDV SDSX16 was characteri...

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Detalles Bibliográficos
Autores principales: Zhao, Pengwei, Wang, Song, Chen, Zhi, Yu, Jiang, Tang, Rongzhi, Qiu, Wenbin, Zhao, Lu, Liu, Yueyue, Guo, Xiaozhen, He, Hongbin, Xu, Guanlong, Li, Jinxiang, Wu, Jiaqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232491/
https://www.ncbi.nlm.nih.gov/pubmed/32244640
http://dx.doi.org/10.3390/v12040391