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Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and differentiation. There is increasing evidence of the therapeutic value of MSCs in various clinical situations, however, these cells gradually lose their regenerative potential with age, with a concomitant increase in cel...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Ding, Yue, Liu, Zhongmin, Liang, Xiaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232554/
https://www.ncbi.nlm.nih.gov/pubmed/32478063
http://dx.doi.org/10.3389/fcell.2020.00258