Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-κB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-κB Pathway in Adjuvant-Induced Arthritis

Rheumatoid arthritis (RA) is among the most prevalent forms of autoimmunity. Gentiopicroside (Gent) is an iridoid glucoside derived from the Gentiana Macrophylla Pall which is used in traditional Chinese medicine to treat RA. The present study was designed to explore the ability of Gent to combat RA...

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Detalles Bibliográficos
Autores principales: Wang, Meiling, Li, Hongyan, Wang, Yanfang, Hao, Yanfei, Huang, Yanan, Wang, Xinlin, Lu, Yongying, Du, Yuan, Fu, Fenghua, Xin, Wenyu, Zhang, Leiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232611/
https://www.ncbi.nlm.nih.gov/pubmed/32477105
http://dx.doi.org/10.3389/fphar.2020.00515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232611/
https://www.ncbi.nlm.nih.gov/pubmed/32477105
http://dx.doi.org/10.3389/fphar.2020.00515

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