Sleep Spindles and Fragmented Sleep as Prodromal Markers in a Preclinical Model of LRRK2-G2019S Parkinson's Disease

Sleep disturbances co-occur with and precede the onset of motor symptoms in Parkinson's disease (PD). We evaluated sleep fragmentation and thalamocortical sleep spindles in mice expressing the p.G2019S mutation of the leucine-rich repeat kinase 2 (LRRK2) gene, one of the most common genetic for...

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Detalles Bibliográficos
Autores principales: Crown, Lindsey M., Bartlett, Mitchell J., Wiegand, Jean-Paul L., Eby, Allison J., Monroe, Emily J., Gies, Kathleen, Wohlford, Luke, Fell, Matthew J., Falk, Torsten, Cowen, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232828/
https://www.ncbi.nlm.nih.gov/pubmed/32477237
http://dx.doi.org/10.3389/fneur.2020.00324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232828/
https://www.ncbi.nlm.nih.gov/pubmed/32477237
http://dx.doi.org/10.3389/fneur.2020.00324

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