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Adherence and Population Pharmacokinetic Properties of Amodiaquine When Used for Seasonal Malaria Chemoprevention in African Children

Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC. Here, we evaluated the population pharmacokinetic properties of amodiaquine and its active metabolite, desethylamodiaquine, in children receiving SMC under directly observed ideal conditions (n...

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Detalles Bibliográficos
Autores principales: Ding, Junjie, Coldiron, Matthew E., Assao, Bachir, Guindo, Ousmane, Blessborn, Daniel, Winterberg, Markus, Grais, Rebecca F., Koscalova, Alena, Langendorf, Celine, Tarning, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232861/
https://www.ncbi.nlm.nih.gov/pubmed/31652336
http://dx.doi.org/10.1002/cpt.1707