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Topologically Guided Prioritization of Candidate Gene Transcripts Coexpressed with the 5-HT(1A) Receptor by Combining In Vivo PET and Allen Human Brain Atlas Data

The serotonin-1A receptor (5-HT(1A)R) represents a viable target in the treatment of disorders of the brain. However, development of psychiatric drugs continues to be hindered by the relative inaccessibility of brain tissue. Although the efficacy of drugs selective for the 5-HT(1A)R has not been pro...

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Detalles Bibliográficos
Autores principales: Unterholzner, Jakob, Gryglewski, Gregor, Philippe, Cecile, Seiger, Rene, Pichler, Verena, Godbersen, Godber M, Berroterán-Infante, Neydher, Murgaš, Matej, Hahn, Andreas, Wadsak, Wolfgang, Mitterhauser, Markus, Kasper, Siegfried, Lanzenberger, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232988/
https://www.ncbi.nlm.nih.gov/pubmed/31989157
http://dx.doi.org/10.1093/cercor/bhz341