Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

BACKGROUND: The presence of calcitonin gene-related peptide and its receptors in multiple brain areas and peripheral tissues previously implicated in migraine initiation and its many associated symptoms raises the possibility that humanized monoclonal anti-calcitonin gene-related peptide antibodies...

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Detalles Bibliográficos
Autores principales: Noseda, Rodrigo, Schain, Aaron J, Melo-Carrillo, Agustin, Tien, Jason, Stratton, Jennifer, Mai, Fanny, Strassman, Andrew M, Burstein, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233263/
https://www.ncbi.nlm.nih.gov/pubmed/31856583
http://dx.doi.org/10.1177/0333102419896760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233263/
https://www.ncbi.nlm.nih.gov/pubmed/31856583
http://dx.doi.org/10.1177/0333102419896760

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