Cargando…
Spirometric traits show quantile-dependent heritability, which may contribute to their gene-environment interactions with smoking and pollution
BACKGROUND: “Quantile-dependent expressivity” refers to a genetic effect that is dependent upon whether the phenotype (e.g., spirometric data) is high or low relative to its population distribution. Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV(1)), and the FEV(1)/FVC ratio...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233273/ https://www.ncbi.nlm.nih.gov/pubmed/32461834 http://dx.doi.org/10.7717/peerj.9145 |