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Down syndrome: Distribution of brain amyloid in mild cognitive impairment

INTRODUCTION: Down syndrome (DS) is associated with a higher risk of dementia. We hypothesize that amyloid beta (Aβ) in specific brain regions differentiates mild cognitive impairment in DS (MCI‐DS) and test these hypotheses using cross‐sectional and longitudinal data. METHODS: 18F‐AV‐45 (florbetapi...

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Detalles Bibliográficos
Autores principales: Keator, David B., Phelan, Michael J., Taylor, Lisa, Doran, Eric, Krinsky‐McHale, Sharon, Price, Julie, Ballard, Erin E., Kreisl, William C., Hom, Christy, Nguyen, Dana, Pulsifer, Margaret, Lai, Florence, Rosas, Diana H., Brickman, Adam M., Schupf, Nicole, Yassa, Michael A., Silverman, Wayne, Lott, Ira T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233421/
https://www.ncbi.nlm.nih.gov/pubmed/32435685
http://dx.doi.org/10.1002/dad2.12013