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Analytical performance of thrombospondin-1 and cathepsin D immunoassays part of a novel CE-IVD marked test as an aid in the diagnosis of prostate cancer

The Prostate Specific Antigen (PSA) test suffers from low specificity for the diagnosis of Prostate Cancer (PCa). We originally discovered two cancer-related proteins thrombospondin-1 (THBS1) and cathepsin D (CTSD) using a mass-spectrometry-based proteomics approach. The two serum proteins were show...

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Detalles Bibliográficos
Autores principales: Macagno, Annalisa, Athanasiou, Alcibiade, Wittig, Anja, Huber, Ramy, Weber, Stephan, Keller, Thomas, Rhiel, Martin, Golding, Bruno, Schiess, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233579/
https://www.ncbi.nlm.nih.gov/pubmed/32421745
http://dx.doi.org/10.1371/journal.pone.0233442