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Sequence-structure-function relationships in class I MHC: A local frustration perspective

Class I Major Histocompatibility Complex (MHC) binds short antigenic peptides with the help of Peptide Loading Complex (PLC), and presents them to T-cell Receptors (TCRs) of cytotoxic T-cells and Killer-cell Immunglobulin-like Receptors (KIRs) of Natural Killer (NK) cells. With more than 10000 allel...

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Detalles Bibliográficos
Autores principales: Serçinoğlu, Onur, Ozbek, Pemra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233585/
https://www.ncbi.nlm.nih.gov/pubmed/32421728
http://dx.doi.org/10.1371/journal.pone.0232849