Cargando…

T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS

BACKGROUND: Schizophrenia (SCZ) is a severe psychiatric disorder affecting ~1% of the world’s population. It is largely heritable with genetic risk reflected by a combination of common variants of small effect and highly penetrant rare mutations. Chromatin modifications are known to play critical ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Farrelly, Lorna, Zhang, Shuangping, Flaherty, Erin, Topol, Aaron, Schrode, Nadine, Bastle, Ryan, Bhanu, Natarajan, Garcia, Benjamin, Li, Haitao, Brennand, Kristen, Maze, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233850/
http://dx.doi.org/10.1093/schbul/sbaa029.569