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T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS
BACKGROUND: Schizophrenia (SCZ) is a severe psychiatric disorder affecting ~1% of the world’s population. It is largely heritable with genetic risk reflected by a combination of common variants of small effect and highly penetrant rare mutations. Chromatin modifications are known to play critical ro...
Autores principales: | Farrelly, Lorna, Zhang, Shuangping, Flaherty, Erin, Topol, Aaron, Schrode, Nadine, Bastle, Ryan, Bhanu, Natarajan, Garcia, Benjamin, Li, Haitao, Brennand, Kristen, Maze, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233850/ http://dx.doi.org/10.1093/schbul/sbaa029.569 |
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