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S181. ANALYSIS OF THE AMELIORATING EFFECT OF D-SERINE ON GLUN2D DEFICIENT MICE

BACKGROUND: The glutamate hypothesis of schizophrenia postulates NMDA receptor (NMDAR) hypofunction as a major pathophysiological mechanism based on clinical observations and preclinical evidence. Mice with globally reduced NMDAR expression display hyperlocomotion, sensorimotor gating deficits, cogn...

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Detalles Bibliográficos
Autores principales: Mallien, Anne, Herb, Anne, Monyer, Hannah, Inta, Dragos, Gass, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234439/
http://dx.doi.org/10.1093/schbul/sbaa031.247