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Hypermutation in single-stranded DNA

Regions of genomic DNA can become single-stranded in the course of normal replication and transcription as well as during DNA repair. Abnormal repair and replication intermediates can contain large stretches of persistent single-stranded DNA, which is extremely vulnerable to DNA damaging agents and...

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Detalles Bibliográficos
Autores principales: Saini, Natalie, Gordenin, Dmitry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234795/
https://www.ncbi.nlm.nih.gov/pubmed/32438271
http://dx.doi.org/10.1016/j.dnarep.2020.102868