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Enhanced Kat3A/Catenin transcription: a common mechanism of therapeutic resistance

Cancers are heterogeneous at the cellular level. Cancer stem cells/tumor initiating cells (CSC/TIC) both initiate tumorigenesis and are responsible for therapeutic resistance and disease relapse. Elimination of CSC/TIC should therefore be able to reverse therapy resistance. In principle, this could...

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Detalles Bibliográficos
Autores principales: Bild, Andrea, Teo, Jia-Ling, Kahn, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234864/
https://www.ncbi.nlm.nih.gov/pubmed/32426696
http://dx.doi.org/10.20517/cdr.2019.32